Publications

2017 Publications

1. Golkowski M, Vidadala RS, Lombard CK, Suh HW, Maly DJ, Ong SE. Kinobead and Single-Shot LC-MS Profiling Identifies Selective PKD Inhibitors. J Proteome Res. 2017. doi: 10.1021/acs.jproteome.6b00817. PubMed PMID: 28102076.

2. McPherson RL, Abraham R, Sreekumar E, Ong SE, Cheng SJ, Baxter VK, Kistemaker HA, Filippov DV, Griffin DE, Leung AK. ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence. Proc Natl Acad Sci U S A. 2017. doi: 10.1073/pnas.1621485114. PubMed PMID: 28143925.

2016 Publications

1. Palazzo L, Daniels CM, Nettleship JE, Rahman N, McPherson RL, Ong SE, Kato K, Nureki O, Leung AK, Ahel I. ENPP1 processes protein ADP-ribosylation in vitro. FEBS J. 2016. doi: 10.1111/febs.13811. PubMed PMID: 27406238.

2. Golkowski M, Shimizu-Albergine M, Suh HW, Beavo JA, Ong SE. Studying mechanisms of cAMP and cyclic nucleotide phosphodiesterase signaling in Leydig cell function with phosphoproteomics. Cell Signal. 2016;28(7):764-78. doi: 10.1016/j.cellsig.2015.11.014. PubMed PMID: 26643407.

3. Bao XR, Ong SE, Goldberger O, Peng J, Sharma R, Thompson DA, Vafai SB, Cox AG, Marutani E, Ichinose F, Goessling W, Regev A, Carr SA, Clish CB, Mootha VK. Mitochondrial dysfunction remodels one-carbon metabolism in human cells. Elife. 2016;5. doi: 10.7554/eLife.10575. PubMed PMID: 27307216; PMCID: PMC4911214.

4. Shimizu-Albergine M, Van Yserloo B, Golkowski MG, Ong SE, Beavo JA, Bornfeldt KE. SCAP/SREBP pathway is required for the full steroidogenic response to cyclic AMP. Proc Natl Acad Sci U S A. 2016;113(38):E5685-93. doi: 10.1073/pnas.1611424113. PubMed PMID: 27601673; PMCID: PMC5035853.

 

2014 Publications

1. Lafranchi L, de Boer HR, de Vries EGE, Ong SE, Sartori AA, van Vugt MATM. APC/C(Cdh1) controls CtIP stability during the cell cycle and in response to DNA damage. EMBO J [Internet]. 2014/10/29 ed. 2014;33(23):2860–79. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25349192 PMID: 25349192

2. Lau HT, Suh HW, Golkowski M, Ong SE. Comparing SILAC- and stable isotope dimethyl-labeling approaches for quantitative proteomics. J Proteome Res. 2014;13(9):4164–4174. PMID: 25077673

3. Yao J, Ong SE, Bajjalieh S. Huntingtin is associated with cytomatrix proteins at the presynaptic terminal. Mol Cell Neurosci [Internet]. 2014/12/03 ed. 2014;63:96–100. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25461618 PMID: 25461618

4. Daniels CM, Ong SE, Leung AKL. Phosphoproteomic approach to characterize protein mono- and poly(ADP-ribosyl)ation sites from cells. J Proteome Res. 2014;13(8):3510–3522. PMID: 24920161

5. Lau HT, Lewis KA, Ong SE. Quantifying in vivo, site-specific changes in protein methylation with SILAC. Methods Mol Biol [Internet]. 2014/07/26 ed. 2014;1188:161–175. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25059611 PMID: 25059611

6. Golkowski M, Brigham JL, Perera GK, Romano GE, Maly DJ, Ong SE. Rapid profiling of protein kinase inhibitors by quantitative proteomics. Medchemcomm [Internet]. 2014/03/22 ed. 2014 [cited 2014 Mar 6];5(3):363–369. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24648882 PMID: 24648882

2015 Publications

1. Daniels CM, Thirawatananond P, Ong SE, Gabelli SB, Leung AK. Nudix hydrolases degrade protein-conjugated ADP-ribose. Sci Rep. 2015;5:18271. doi: 10.1038/srep18271. PubMed PMID: 26669448; PMCID: PMC4680915.

2. Daniels CM, Ong SE, Leung AK. The Promise of Proteomics for the Study of ADP-Ribosylation. Mol Cell. 2015;58(6):911-24. doi: 10.1016/j.molcel.2015.06.012. PubMed PMID: 26091340; PMCID: PMC4486045.

 

2013 Publications

1. Lee MN, Roy M, Ong SE, Mertins P, Villani A-C, Li W, Dotiwala F, Sen J, Doench JG, Orzalli MH, Kramnik I, Knipe DM, Lieberman J, Carr SA, Hacohen N. Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach. Nat Immunol [Internet]. 2012/12/25 ed. 2013 Dec 23 [cited 2012 Dec 26];14(2):179–85. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23263557 PMID: 23263557

2. Rensvold JW, Ong SE, Jeevananthan A, Carr SA, Mootha VK, Pagliarini DJ. Complementary RNA and protein profiling identifies iron as a key regulator of mitochondrial biogenesis. Cell Rep [Internet]. 2013/01/16 ed. 2013;3(1):237–245. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23318259 PMID: 23318259